Organisers say the Opening Ceremonies will pay tribute to America, Kentucky, and the equine world.
Mares and foals loose in the Aachen arena made for a spectacular display during the WEG opening ceremony in 2006.
"We will highlight both the best of Kentucky and the best of America, and begin these Games with incredible celebration and fanfare."
As many as 600 performers and 200 horses could be involved in the production, including a 100-piece orchestra, 300-person choir and hundreds of adults and children. Marching bands, performing ensembles from America's armed forces, and local and international celebrities and dignitaries are likely to be involved.
The production will include a tribute to American music, including Broadway and Bluegrass, the official Parade of Athletes and, in tribute to the first American host, a singing of My Old Kentucky Home.
Opening Ceremonies will be held September 25, 2010 at 7pm in the Outdoor Stadium at the Kentucky Horse Park, the venue for the Games. Closing Ceremonies will be celebrated in the same location, on October 10 at 4pm.
"Our Opening Ceremonies will set the tone for 16 days of world-class competition," said Jamie Link, CEO of the World Games 2010 Foundation.
"These Games will be the largest sporting event in America in 2010, and we hope to stage an Opening Ceremonies that reflects the magnitude of this event on Kentucky, America, and the equestrian world."